Table 2. Association between miR-125b expression and clinicopathological characteristics in epithelial ovarian cancer.
| Parameter | Number n(%) | miR-125b ExpressionHigh (n)(%) | p-value |
|---|---|---|---|
| Age (years) | |||
| ≤45 | 40 (57.1) | 17 (42.5) | 0.13 |
| >45 | 30 (42.8) | 19 (63.3) | |
| Histological grade | |||
| Well | 25 (35.7) | 12 (48.0) | 0.04 |
| Moderate | 26 (37.1) | 18 (69.2) | |
| Poor | 19(27.1) | 6 (31.5) | |
| Histological type | |||
| Mucinous | 36(51.4) | 18 (50.0) | 0.31 |
| Serous | 17 (24.2) | 11 (64.7) | |
| Papillary | 8 (11.4) | 2 (25.0) | |
| Others | 9 | 5 (55.5) | |
| Tumor size | |||
| <10 cm3 | 5(7.1) | 4 (80.0) | 0.22 |
| 10–50 cm3 | 7(10.0) | 5(71.4) | |
| 50–200 cm3 | 14(20.0) | 9 (64.2) | |
| 200–500 cm3 | 17(24.2) | 7 (41.1) | |
| >500 cm3 | 27(38.5) | 11 (40.7) | |
| FIGO stage | |||
| I | 23(32.8) | 23 (100.0) | <0.0001 |
| II | 10(14.2) | 10 (100.0) | |
| III | 19(27.1) | 2 (10.5) | |
| IV | 18(25.7) | 1 (5.5) | |
| Distant metastasis | |||
| Absent | 52(74.2) | 35 (67.3) | 0.002 |
| Present | 18 (25.7) | 1 (5.0) | |
| Lymph node status | |||
| Absent | 51(72.8) | 33 (64.7) | 0.001 |
| Present | 19(27.1) | 3 (15.7) | |
| Menopause | |||
| Pre | 39(55.7) | 17 (43.5) | 0.21 |
| Post | 31(44.2) | 19 (61.2) | |
| Nulliparity | |||
| Absent | 51(44.2) | 30 (58.8) | 0.07 |
| Present | 19(27.1) | 6 (31.5) | |
| Serum CA125 (U/ml) | |||
| ≤35 | 9(11.4) | 5 (55.5) | 0.92 |
| >35 | 61(88.5) | 31 (50.8) | |
| Hemoglobin (gm/dL) | |||
| ≤12 | 59(84.2) | 30 (50.8) | 0.92 |
| >12 | 11(15.7) | 6 (54.5) |