Table 1.
Characteristics of Women Who Received Influenza Vaccination, by Age Group and Human Immunodeficiency Virus (HIV) Status
Characteristic | Young Women |
Older Women |
||
---|---|---|---|---|
HIV Uninfected (n = 15) | HIV Infected (n = 15) | HIV Uninfected (n = 20) | HIV Infected (n = 20) | |
Age, y | 32.9 ± 4.4 | 37.9 ± 4.7 | 65 ± 4.9 | 61.5 ± 3 |
Vaccine responder, % | 60 | 47 | 30 | 35 |
Vaccine nonresponder, % | 40 | 53 | 70 | 65 |
CD4+ T-cell count, cells/µL | ND | 654.3 ± 313.8 | ND | 602.7 ± 273.6 |
Seroprotection | ||||
Before vaccination, % | 68.6 | 56.6 | 50 | 25 |
4 wks after vaccination, % | 100 | 93.3 | 75 | 55 |
HAI titer | ||||
Before vaccination | 64 ± 44.2a,b | 36 ± 22.6a | 58 ± 59.2a | 22.5 ± 10.6 |
4 wks after vaccination | 328 ± 338.8a,b,c | 100 ± 53.9a | 96.5 ± 83.9a | 56 ± 48.08 |
Data are mean value ± SD or percentage of subjects.
Abbreviations: HAI, hemagglutination inhibition; ND, not determined; SD, standard deviation.
a Statistically significantly different from older HIV-infected women.
b Statistically significantly different from young HIV-infected women.
c Statistically significantly different from older HIV-uninfected women.