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. 2015 Jun 10;107(9):djv159. doi: 10.1093/jnci/djv159

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Published by Oxford University Press 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 1. — Observed and projected incidence of invasive and in situ estrogen receptor (ER)–positive breast tumors in Surveillance, Epidemiology, and End Results (SEER) 13 and corresponding forecasts of cancer burden in the entire United States. A) Observed and projected incidence of invasive ER+ tumors per 100 000 woman-years in SEER 13. B) Predicted burden of invasive ER+ tumors in the United States (number of newly diagnosed cases per year) by age group and overall. C) Observed and projected incidence of in situ ER+ tumors per 100 000 woman-years in SEER 13. D) Predicted burden of in situ ER+ tumors in the entire United States. In each panel, circles show point estimates for each year. Shaded bands show point-wise 95% confidence limits. Vertical reference line separates observed from forecast period. ER = estrogen receptor.