Table 2.
Total volume of neocortex, hippocampus and its subregions*.
| Brain Region | Group | (n) | Mean (mm3) | 95% CI | CE (m=0) | CE2/CV2 |
|---|---|---|---|---|---|---|
| Neocortex | control | (7) | 45.4 | [39.4 , 51.3] | 0.04 | 8% |
| lithium | (9) | 45.1 | [38.0 , 52.2] | 0.04 | 4% | |
| Hippocampus | control | (7) | 11.19 | [10.24 , 12.14] | 0.01 | 2% |
| lithium | (9) | 10.73 | [ 9.63 , 11.83] | 0.01 | 1% | |
| CA1 | control | (7) | 3.27 | [ 2.84 , 3.69] | 0.08 | 29% |
| lithium | (9) | 3.17 | [ 2.87 , 3.47] | 0.03 | 5% | |
| CA2-3 | control | (7) | 3.24 | [ 2.99 , 3.49] | 0.07 | 69% |
| lithium | (9) | 3.01 | [ 2.65 , 3.37] | 0.05 | 11% | |
| Dentate Gyrus | control | (7) | 2.19 | [ 2.01 , 2.37] | 0.07 | 47% |
| lithium | (9) | 2.09 | [ 1.84 , 2.34] | 0.03 | 3% | |
| Hilus | control | (7) | 0.295 | [ 0.271 , 0.320] | 0.16 | 2.47% |
| lithium | (9) | 0.291 | [ 0.265 , 0.318] | 0.12 | 1.01% | |
| Subiculum | control | (7) | 2.20 | [ 1.96 , 2.44] | 0.12 | 81% |
| lithium | (9) | 2.17 | [ 1.91 , 2.43] | 0.05 | 11% |
*
left plus right hemisphere values
CE: Coefficient of Error (see for m=0 the text in Materials & Methods); CI: Confidence Interval; CV: Coefficient of Variation (sd/mean)