Table 2.
Changes in Cardiopulmonary Exercise Testing Parameters and Quality of Life by Pacing and Exercise Group
| Parameter | No device | RV pacing | BiV pacing | |||
|---|---|---|---|---|---|---|
| Usual care n=629 |
Exercise n=584 |
Usual Care n=332 |
Exercise n= 351 |
Usual Care n= 211 |
Exercise n=224 |
|
| CPX duration (min) at baseline | 10.0 n=620 (7.0, 12.8) |
9.8 n=580 (7.0, 12.0) |
9.5 n=330 (7.0, 12.0) |
9.3 n=346 (6.5, 12.0) |
9.0 n=210 (6.7, 11.1) |
9.1 n=223 (6.6, 11.6) |
| At 3 months | 10.5 n=466 (7.5, 13.3) |
11.6 n=495 (9.0, 14.5) |
9.8 n=274 (7.4, 12.3) |
10.8 n=300 (8.3, 13.7) |
9.3 n=167 (7.5, 11.7) |
10.6 n=192 (8.1, 14.0) |
| Peak VO2 at baseline (ml/kg/min) | 15.1 n=613 (12.1, 18.7) |
14.7 n=580 (11.5, 18.0) |
14.1 n=325 (12.2, 17.1) |
14.3 n=335 (11.0, 17.4) |
13.9 n=205 (11.3, 16.6) |
13.8 n=217 (11.3, 16.9) |
| At 3 months | 15.6 n=456 (12.4, 19.4) |
15.9 n=489 (12.6, 19.1) |
14.5 n=269 (11.5, 17.5) |
15.1 n=288 (11.7, 18.4) |
13.9 n=162 (11.7, 16.8) |
14.9 n=187 (12.1, 18.3) |
| KCCQ overall at baseline | 70 n=628 (51, 85) |
69 n=584 (51, 85) |
68 n=332 (51, 84) |
67 n=351 (52, 82) |
67 n=211 (53, 82) |
63 n=224 (47, 79) |
| At 3 months | 75 n=498 (56, 89) |
76 n=511 (59, 90) |
72 n=282 (55, 86) |
73 n=317 (58, 88) |
71 n=185 (55, 82) |
72 n=209 (52, 85) |
| Pro-BNP at baseline (pg/ml) | 621.4 n=373 (278.4, 1484) |
582.4 n=357 (221.7, 1313) |
980.7 n=194 (459.7, 2069) |
924.1 n=207 (406.7, 2171) |
1315 n=120 (509.6, 2694) |
1236 n=132 (528.7, 3023) |
| At 3 months | 558.0 n=272 (219.9, 1581) |
480.8 n=260 (183.7, 1264) |
959.8 n=144 (418.9, 1949) |
998.2 n=159 (410.2, 2399) |
881.5 n=93 (367.3, 1975) |
1197 n=116 (522.5, 2801) |
*
Continuous variables show as median (25th, 75th percentiles). These data represent the overall results and are not adjusted for missing data.