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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: J Cell Physiol. 2016 Feb 8;231(8):1761–1770. doi: 10.1002/jcp.25279

Figure 9. Effects of OA knock-down on OSCC cell proliferation and migration.

Figure 9

OSCC cells were treated with OA- or scramble siRNAs to assess effects of OA RNA interference on cell proliferation and migration. (A) OA knock-down was confirmed with Western blot analysis and was more pronounced for SCC25 cells than for SCC15 cells. (B) OA knock-down significantly inhibited proliferation in both cell lines. In SCC15 cells, proliferation of scramble siRNA-transduced cells exceeded that of OA siRNA-transduced cells by day 4 (p=0.008) and continued into day 6 (p<0.0001). For SCC25 cells proliferation of scramble siRNA-transduced cells exceeded that of OA siRNA-transduced cells on days 2–6 (p<0.0001 for the three time points). (C) OA knock-down did not inhibit cell migration in uncoated dishes.