Table 2.

Angulations of aggregated cardiomyocytes

	Endocardium (0–33%)				Midwall (33–66%)				Epicardium (66–100%)				Transmural total (0–100%)
	PPHN	Control	Difference	P value	PPHN	Control	Difference	P value	PPHN	Control	Difference	P value	PPHN	Control	Difference	P value
Left ventricle	17.5 (3.2)	15.8 (3.3)	1.7	NS	14.0 (3.3)	11.5 (3.0)	2.5	<0.001	15.7 (3.2)	12.3 (3.3)	3.4	<0.001	15.7 (3.2)	13.0 (3.2)	2.7	<0.001
Right ventricle	12.1 (3.2)	13.5 (3.1)	−1.4	NS	11.1 (3.2)	8.5 (3.0)	2.6	<0.001	12.3 (3.2)	10.8 (3.2)	1.5	<0.001	11.8 (3.2)	10.7 (3.1)	1.1	<0.001
Septum	19.6 (3.0)	12.2 (3.3)	7.4	<0.001	15.4 (3.0)	12.4 (3.2)	3	0.001	12.6 (3.2)	11.8 (3.1)	0.8	NS	15.6 (3.1)	12.1 (3.2)	3.5	<0.001
Entire heart	16.1 (3.2)	14.2 (3.2)	1.9	<0.001	13.4 (3.2)	10.6 (3.1)	2.8	<0.001	13.7 (3.2)	11.7 (3.2)	2	<0.001	14.3 (3.2)	12. 1(3.2)	3.5	<0.001

Post-hoc analysis based on myocardial depth with Bonferroni correction for multiple comparisons. All transmural levels are cumulated in the “Transmural total” column. Septal endocardium is the left ventricular endocardium while septal epicardium refers to the right ventricular endocardium. Data are shown as mean values (SD).

NS, statistically nonsignificant; PPHN, persistent pulmonary hypertension of the newborn.