Table 2.
Odds ratios for early treatment discontinuation (before day 100 after the first dispensed MPH prescription).
Differences in patient-related factors between individuals with and without on going MPH treatment day 100.
| Total (N=4280) % |
Discontinuation < 100 (N=1134) % |
ORc (95% CI) | |
|---|---|---|---|
| Male | 64.4 | 67.3 | 1.19 (1.03–1.38) |
| Female | 35.6 | 32.7 | ref=1 |
| Age | |||
| 18–26 | 27.0 | 29.8 | 1.20 (1.01–1.42) |
| 27–39 | 38.6 | 36.9 | 0.98 (0.84–1.16) |
| 40–59 | 34.3 | 33.2 | ref=1 |
| Comorbid Psychiatric Disorder | |||
| None of following | 29.9 | 31.2 | 1.09 (0.94–1.26) |
| Schizophrenia | 3.2 | 3.5 | 1.13 (0.77–1.64) |
| Mood or anxiety disorders | 63.3 | 62.0 | 0.92 (0.80–1.06) |
| Eating disorders | 3.5 | 2.5 | 0.63 (0.42–0.96) |
| Personality disorders/Conduct disorder | 28.5 | 28.9 | 1.03 (0.89–1.20) |
| Prescribing Physician’s Specialty | |||
| Addiction | 19.3 | 20.5 | 1.28 (1.01–1.62) |
| Psychiatry | 72.0 | 69.5 | ref=1 |
| Other | 8.7 | 10.1 | 1.14 (0.96–1.35) |
| SUD Diagnosis | |||
| ATC-code SUD medication | 9.0 | 8.4 | 0.85 (0.64–1.12) |
| Alcohol Use Disorder | 56.1 | 59.1 | ref=1 |
| Stimulant Use Disordera | 17.9 | 18.7 | 0.98 (0.81–1.18) |
| Combinedb | 15.0 | 16.1 | 0.88 (0.73–1.07) |
a
F14 Amphetamine Use Disorder and F15 Cocaine Use Disorder
b
Substance Use Disorder including F11 OpiatesF12 Cannabis, F13 Hypnotics and Sedatives, F16 Hallucinogens, F18 Inhalants, F19 Several drugs in combination.
c
ORs adjusted for all covariates listed in the table