Table 1. Baseline Characteristics of Trial Participants.
| Demographics | No. (%) | p value‡ | ||||||
|---|---|---|---|---|---|---|---|---|
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| Placebo (n=15) | Naltrexone (n=15) | Overall (n=30) | ||||||
| Age, mean (SD), y | 42.3 | (10.0) | 43.7 | (8.8) | 43 | (9.3) | 0.54 | |
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| Race/Ethnicity | ||||||||
| White | 6 | (40.0) | 6 | (40.0) | 12 | (40.0) | ≥ 0.99 | |
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| African-American | 5 | (33.3) | 4 | (26.7) | 9 | (30.0) | ||
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| Latino | 2 | (13.3) | 3 | (20.0) | 5 | (16.7) | ||
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| Asian and Pacific Islander | 1 | (6.7) | 1 | (6.7) | 2 | (6.7) | ||
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| Other | 1 | (6.7) | 1 | (6.7) | 2 | (6.7) | ||
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| Education | ||||||||
| High school or less | 2 | (13.3) | 2 | (13.3) | 4 | (13.3) | ≥ 0.99 | |
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| Some college | 8 | (53.3) | 9 | (60.0) | 17 | (56.7) | ||
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| College or above | 5 | (33.3) | 4 | (26.7) | 9 | (30.0) | ||
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| Income | ||||||||
| under $20,000 | 9 | (60.0) | 9 | (60.0) | 18 | (60.0) | 0.68 | |
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| $20,000-39,999 | 3 | (20.0) | 5 | (33.3) | 8 | (26.7) | ||
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| $40,000 and above | 3 | (20.0) | 1 | (6.7) | 4 | (13.3) | ||
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| refused to answer | 1 | (6.7) | 1 | (6.7) | 2 | (6.7) | ||
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| Employment status | ||||||||
| Not employed | 8 | (53.3) | 13 | (86.7) | 21 | (70.0) | 0.13 | |
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| Part-time | 3 | (20.0) | 2 | (13.3) | 5 | (16.7) | ||
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| Full-time | 3 | (20.0) | 0 | 0.0 | 3 | (10.0) | ||
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| Employed student | 1 | (6.7) | 0 | 0.0 | 1 | (3.3) | ||
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| Alcohol Use | ||||||||
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| Frequency of alcohol use (past 4 weeks) | ||||||||
| 1 day per week or less | 1 | (6.7) | 5 | (33.3) | 6 | (20.0) | 0.17 | |
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| 2 days per week or more | 14 | (93.3) | 10 | (66.7) | 24 | (80.0) | ||
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| Alcohol use during sex (past 4 weeks) | ||||||||
| 50% or less of the time | 8 | (53.3) | 11 | (73.3) | 19 | (63.3) | 0.45 | |
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| Greater than 50% of time | 7 | (46.7) | 4 | (26.7) | 11 | (36.7) | ||
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| Number of Drinks in Typical Drinking Days (past 4 weeks), mean (SD) | 5.9 | (2.2) | 5.1 | (2.9) | 5.5 | (2.5) | 0.32 | |
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| Number of Binge Drinking Days (past 4 weeks), mean (SD) | 9.3 | (9.0) | 3.9 | (3.1) | 6.6 | (7.2) | 0.13 | |
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| Alcohol visual analog scale (VAS) craving score, mean (SD) | 59.3 | (26.0) | 38.9 | (29.3) | 49.1 | (29.1) | 0.06 | |
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| History of alcohol self-help or treatment program | 6 | (40.0) | 10 | (66.7) | 16 | (53.3) | 0.27 | |
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| Methamphetamine use | ||||||||
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| Frequency of methamphetamine use (past 4 weeks) | ||||||||
| less than 1 day per week | 6 | (40.0) | 10 | (66.7) | 16 | (53.3) | 0.47 | |
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| at least 1 day per week | 9 | (60.0) | 5 | (33.3) | 14 | (46.7) | ||
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| Methamphetamine use during sex (past 4 weeks) | ||||||||
| 50% or less of the time | 10 | (66.7) | 11 | (73.3) | 21 | (70.0) | ≥0.99 | |
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| More than 50% of time | 5 | (33.3) | 4 | (26.7) | 9 | (30.0) | ||
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| Methamphetamine visual analog scale (VAS) craving score, mean (SD) | 41.6 | (23.0) | 35.7 | (25.5) | 38.7 | (24.1) | 0.53 | |
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| History of methamphetamine self-help or treatment program | 6 | (40.0) | 10 | (66.7) | 16 | (53.3) | 0.27 | |
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| Clinical | ||||||||
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| HIV serostatus | HIV positive | 5 | (33.3) | 7 | (46.7) | 12 | (40.0) | 0.71 |
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| HIV negative | 10 | (66.7) | 8 | (53.3) | 18 | (60.0) | ||
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| Has regular health care provider | 10 | (66.7) | 10 | (66.7) | 20 | (66.7) | ≥0.99 | |
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| Has health insurance | 11 | (73.3) | 12 | (80.0) | 23 | (76.7) | ≥0.99 | |
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| Center for epidemiologic studies depression scale (CES-D) score, mean (SD) | 18.1 | (7.5) | 20.3 | (13.9) | 19.2 | (11.0) | 0.76 | |
‡
binary and categorical characteristics compared using the Fisher's exact test, and group medians compared using the Wilcoxon rank-sum test