Table 2.
Effects of recurrent NTG migraine episodes on behavioral endpoints
| Endpoints | 0-NTG (5 Saline) | 3-NTG (2 Saline) | 5-NTG |
|---|---|---|---|
| % Change Body Weight | 21.76 (3.21) | 14.93* (7.49) | 13.42* (4.35) |
| Grimace Score | .075 (.105) | .138 (.181) | .20 (.206) |
| Cool-Tailflick Latency (s) | 16.5 (12.4) | 23.0 (18.3) | 20.1 (15.6) |
| Warm-Tailflick Latency (s) | 9.8 (5.3) | 10.4 (3.4) | 13.2 (12.5) |
| EPM-Time in Open Arms (s) | 13.0 (19.3) | 17.4 (16.7) | 16.2 (22.9) |
| FST-Float Time (s) | 136.3 (36.1) | 144.5 (41.4) | 112.9 (46.0) |
Mean (SD); EPM elevated plus maze. FST forced swim test
*p < .05 vs 0-NTG control