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. 2016 Mar 11;408:3547–3553. doi: 10.1007/s00216-016-9431-1

Table 2.

Precision of retention times for histone H4-derived peptides after chymotrypsin and trypsin digestion analyzing six replicates spread over three different days

Measured peptide forms Average retention time (n = 18) Relative standard deviation (%)
[+d0-/d6-]GK[+56.0]GGK[+56.0]GL 17.688 0.028
[+d0-/d6-]GK[+56.0]GGAK[+56.0]R 13.610 0.000
[+d0-/d6-]GK[+42.0]GGK[+56.0]GL 16.848 0.010
[+d0-/d6-]GK[+56.0]GGK[+42.0]GL 17.077 0.044
[+d0-/d6-]GK[+42.0]GGAK[+42.0]R 12.781 0.096
[+d0-/d6-]GK[+42.0]GGAK[+56.0]R 13.176 0.039
[+d0-/d6-]GK[+56.0]GGAK[+42.0]R 13.180 0.000
[+d0-/d6-]GK[+56.0]GGK[+56.0]GL 17.694 0.045
[+d0-/d6-]GK[+56.0]GGAK[+56.0]R 13.611 0.014
[+d0-/d6-]GK[+42.0]GGK[+56.0]GL 16.853 0.034
[+d0-/d6-]GK[+56.0]GGK[+42.0]GL 17.091 0.265
[+d0-/d6-]GK[+42.0]GGAK[+42.0]R 12.780 0.117
[+d0-/d6-]GK[+42.0]GGAK[+56.0]R 13.167 0.101
[+d0-/d6-]GK[+56.0]GGAK[+42.0]R 13.181 0.015

The levels refer to the following (d0-/d6-) mixing ratios: 0.5:1 (upper part) and 0.3:1 (lower part)