Table 1.
Patient demographics and tumour characteristics of all 910 patients and divided per centre
| MUMC N = 154 | CWZ N = 171 | NKI N = 428 | CZE N = 157 | Total N = 910 | |
|---|---|---|---|---|---|
| Median age in years (range) | 60 (33–84) | 58 (32–81) | 55 (27–90) | 58 (30–80) | 57 (27–90) |
| DCIS biopsy (%) | |||||
| Grade 1 | 31 (20.1) | 26 (15.2) | 110 (25.7) | 33 (21.0) | 200 (22.0) |
| Grade 2 | 67 (43.5) | 45 (26.3) | 189 (44.2) | 47 (29.9) | 348 (38.2) |
| Grade 3 | 56 (36.4) | 100 (58.5) | 129 (30.1) | 77 (49.1) | 362 (39.8) |
| Palpable mass (%) | 27 (17.5) | 12 (7.0) | 40 (9.3) | 1 (0.6) | 80 (8.8) |
| Mammography (%) | |||||
| No abnormalities | 7 (4.5) | 5 (2.9) | 9 (2.1) | 1 (0.6) | 22 (2.4) |
| Calcifications | 117 (76.0) | 160 (93.6) | 360 (84.1) | 146 (93.0) | 783 (86.0) |
| Mass | 13 (8.5) | – | 10 (2.3) | 3 (1.9) | 26 (2.9) |
| Calcification and mass | 17 (11.0) | 6 (3.5) | 49 (11.5) | 7 (4.5) | 79 (8.7) |
| Ultrasound (%) | |||||
| In total performed | 154 (100) | 154 (90.1) | 295 (68.9) | 157 (100) | 761 (83.6) |
| No abnormalities | 101 (65.6) | 118 (76.6) | 128 (43.4) | 134 (85.4) | 481 (63.3) |
| Benign lesion | 1 (0.6) | 3 (2.0) | 4 (1.4) | 1 (0.6) | 9 (1.2) |
| Suspect lesion | 32 (20.8) | 16 (10.4) | 124 (42.0) | 19 (12.1) | 191 (25.1) |
| Other | 20 (13.0) | 17 (11.0) | 39 (13.2) | 3 (1.9) | 79 (10.4) |
| MRI (%) | |||||
| In total performed | 105 (68.2) | 10 (5.8) | 285 (66.6) | 9 (5.7) | 409 (44.9) |
| No abnormalities | 17 (16.2) | – | 103 (36.1) | 3 (33.3) | 123 (30.0) |
| Non mass like enhanced | 64 (61.0) | 7 (70.0) | 157 (55.1) | 5 (55.6) | 233 (57.0) |
| Massa enhanced | 19 (18.0) | 1 (10.0) | 21 (7.4) | 1 (11.1) | 42 (10.3) |
| Asymmetry | 5 (4.8) | 2 (20.0) | 4 (1.4) | – | 11 (2.7) |
| Operation (%) | |||||
| Lumpectomy | 66 (42.9) | 100 (58.5) | 223 (52.1) | 126 (80.3) | 515 (56.6) |
| Mastectomy | 88 (57.1) | 71 (41.5) | 205 (47.9) | 31 (19.7) | 395 (43.4) |
MUMC Maastricht University Medical Centre, Maastricht, CWZ Canisius-Wilhelmina Hospital, Nijmegen, NKI Netherlands Cancer Institute, Amsterdam, CZE Catharina Hospital, Eindhoven, DCIS Ductal carcinoma in situ, MRI Magnetic Resonance Imaging