Table 1.

Information about the type of material available on the SEARCHBreast portal

Mouse information	Tissue availablea	Phenotypes	Analysis performed
Model name, cell line, Jax stock number, GEM allele, transplantation site, strain, sex	Tumour, lung, mammary fat pad, lymph node, heart, spleen, liver, long bones, skull, serum, vertebrae, circulating DNA embryos, sperm, live animals,	ER/PR/HER2 status, metastasis sites metastatic penetrance CK5/CK8/p63/SMA status	Tumour volume, general histology, vascularisation, immune infiltrate, apoptosis, proliferation, transcriptome analysis, metastatic assay, microenvironment analysis

^aMany of the tissues available are stored as formalin-fixed paraffin-embedded, frozen, or as histological slides, enabling user-friendly samples to be sent ready for immediate use by scientists