Table 4.
Linear regression analyses for mean relative total dose intensity
| Univariate model | Multivariate model | |||
|---|---|---|---|---|
| Coefficient (SE) | p value | Coefficient (SE) | p value | |
| Mean RTDI anthracyclines (%) | ||||
| BRCA1/2 versus sporadic | 1.69 (1.08) | 0.12 | Not applicablec | |
| Age at start chemotherapy | −0.05 (0.03) | 0.12 | ||
| Previous chemotherapya | −1.09 (1.84) | 0.55 | ||
| Radiotherapy before chemotherapyb | −1.16 (1.00) | 0.25 | ||
| Mean RTDI taxanes (%) | ||||
| BRCA1/2 versus sporadic | 3.94 (2.98) | 0.19 | 3.33 (2.97) | 0.26 |
| Age at start chemotherapy | −0.10 (0.08) | 0.22 | – | – |
| Previous chemotherapya | 6.71 (4.17) | 0.11 | – | – |
| Radiotherapy before chemotherapyb | −6.77 (2.75) | 0.01 | −6.50 (2.76) | 0.02 |
RTDI Relative total dose intensity, SE standard error
a Versus no previous chemotherapy
b Versus no radiotherapy before chemotherapy
c None of the variables were associated with the outcome variable