Figure 3.

Mean immunoglobulin (Ig)G trough (pre‐dose) levels following Gammaplex 5% infusion to infusion 12. Because the last infusion for subjects on the 28‐day dosing schedule was infusion 12, data for infusions 13–17 (available for the 21‐day dosing schedule only) are not shown. Threshold at 6·00 g/l (minimum trough serum IgG level for inclusion in study) is indicated by the grey line. Screening (visit 1) blood samples were not included, as not all sampling was at trough (some were taken mid‐cycle). Patients on the 21‐day schedule had their 10th infusion delayed to accommodate the 28‐day blood sampling, as illustrated by the consistent dip in concentrations at infusion 10.