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. 2016 Apr 6;2016:2953072. doi: 10.1155/2016/2953072

Figure 3.

Figure 3

The relationship between serum levels of κ/λ hybrid antibody and RA-related clinical parameters. (a) Levels of κ/λ hybrid antibody in the serum of RA patients correlated with RF (r = 0.53, p = 0.0003). (b) Levels of κ/λ hybrid antibody were significantly higher in ACPA(+) than ACPA(−) group with p = 0.0065; the differences of κ/λ hybrid antibody levels between groups were assessed using the Mann-Whitney U test; solid line was labeled at mean with SEM, ∗∗ p < 0.01. (c, d) Levels of κ/λ hybrid antibody in the serum of RA patients correlated with IFN-γ (r = 0.44, p = 0.024) and D-dimer (r = 0.54, p < 0.0001). Concentrations of κ/λ hybrid antibody are presented in arbitrary units (AU/mL). Symbols represent individual subjects. Correlations were determined by Spearman's rank correlation coefficients with 95% confidence interval.