Table 2.

Effect of melatonin on retinal function. The average amplitudes of scotopic and photopic ERG a-wave and b-wave at 12 wk of treatment were shown. These parameters were significantly reduced in diabetic animals as compared with the control groups, whereas the amplitudes decrease could be inhibited by melatonin treatment. ND, age-matched nondiabetic group; D12, diabetic group at 12 weeks; DM12, melatonin-treated diabetic group at 12 weeks. ^∗ P < 0.05 when compared with the ND group; ^# P < 0.05 when compared with the diabetic group.

Groups	a-wave (uV) (mean ± SD)		b-wave (uV) (mean ± SD)
	Scotopic ERG	Photopic ERG	Scotopic ERG	Photopic ERG
ND	−122.02 ± 41.29	−37.43 ± 5.54	294.14 ± 28.61	395.83 ± 13.12
D12	−64.52 ± 23.76∗	−24.21 ± 3.43∗	193.27 ± 14.95∗	158.47 ± 19.18∗
DM12	−121.13 ± 33.08 #	−28.03 ± 3.69	273.48 ± 19.81#	277.36 ± 24.39