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. 2016 Apr 20;6:24607. doi: 10.1038/srep24607

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(A) Mutational signature of all SNVs. All substitutions are referred to by the pyrimidine context of the mutated base pair. (B) Genomic evolution of COLO829. A schematic of unique somatic alterations across each truth set is shown. Separate lobes reflect the level of divergence demonstrated by each truth set as measured by the number of unique somatic SNVs and indels for that data set. Examples of unique events are shown. The Pleasance sample did not demonstrate unique coding SNVs or indels (chromosomal coordinates of unique intronic events are shown).