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. 2016 Apr 20;6:24851. doi: 10.1038/srep24851

Figure 3. Injury paradigms stimulate regenerative response signatures that exhibit both commonality and uniqueness.

Figure 3

Fish were given an intraperitoneal injection of BrdU at 2 dpi and then sacrificed at 2 dpi (3 hours post BrdU injection), 4, 7, 14 and 30 dpi. (A–C) BrdU+ nuclei were counted and the percentage of BrdU+ nuclei residing in the (A) ONL, (B) INL and (C) GCL was determined for individual samples for each injury model. Data represents means ± s.d. (n ≥ 3). *P < 0.04549. (D–I) Representative images of retinal sections analyzed in (A–C) that were immunostained for BrdU at (D–F) 2 dpi or (G–I) 30 dpi following (D,G) needle poke, (E,H) PA or (F–I) NMDA injury. Scale bar is equal to 50 μm. Abbreviations are as in Fig. 1.