Table 2.
Ishak fibrosis stage | Cut-off (kPa) | AUROC | P value | Sensitivity | Specificity | PPV | NPV |
≥ F1 | 4.75 | 0.807 | 0.039 | 81.4 | 75.0 | 98.6 | 15.7 |
≥ F2 | 6.65 | 0.947 | < 0.0001 | 88.7 | 86.5 | 90.4 | 84.2 |
≥ F3 | 8.25 | 0.960 | < 0.0001 | 89.5 | 90.4 | 87.2 | 92.2 |
≥ F4 | 13.0 | 0.993 | < 0.0001 | 100 | 96.9 | 92.9 | 100 |
≥ F5 | 18.0 | 0.985 | < 0.0001 | 100 | 97.2 | 90.0 | 100 |
F6 | 29.5 | 0.941 | < 0.0001 | 85.7 | 91.6 | 46.2 | 98.7 |
AUROC: Area under receiver operating characteristic curve; PPV: Positive predictive value; NPV: Negative predictive value.