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. 2016 Apr 18;7:11344. doi: 10.1038/ncomms11344

Figure 1. Sequence alignment of the LDLa-linker and domain structure of RXFP1.

Figure 1

(a) Alignment of the sequences of the LDLa module and the 32-residue linker connecting to the LRR domain. Organisms shown human, rhesus (Macaca mulatta), Gibbon (Nomascus leucogenys), Orangutan (Pongo abelii), Horse (Equus caballus), Mouse (Mus musculus), Rat (Rattus norvegicus), Shrew (Tree Shrew; Tupaia belangeri), Dolphin (Tursiops truncatus) and Wallaby (Macropus eugenii). Sequences are from Genebank. (b) Model of the domain structure of RXFP1 showing the known structure of the N-terminal LDLa module (cyan) (pdb 2jm4) and homology models of the LRR (blue) and TM (orange) domains connected by linkers of unknown structure.