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. 2016 Apr 19;9:42. doi: 10.1186/s13041-016-0225-3

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© Min et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — CX3CR1⁺ cells increase in the peri-hematoma region after ICH. a CX3CR1⁺ cells were detected in peri-hematoma regions of hemorrhagic brain sections. b–e Representative images on brain sections were obtained from Cx3cr1 ^+/GFP mice at 1, 3, and 7 days after ICH or sham operation. Three days after ICH, amoeboid cells were detected in the peri-hematoma region (arrows) (Scale bar, 100 μm). f Myeloid cells (F4/80⁺) in the lesion were analyzed and further divided into CD45-low microglia and CD45-high macrophage populations according to the expression level of CD45 according to flow cytometry. The flow cytometry data are representative of three independent experiments