Fig. 5.

Scheme of the HIV-1 genome and position of the Ku-binding site in 5’-LTR. A – positions of the 5’-LTR regions are specified: U3 (nucleotides 1–455), R (456–552), and U5 (553–638) (counting from the beginning of the genome). The major regulatory regions of 5’-LTR are shown. +1 – counting from the transcription initiation site denoted by an arrow. The Ku-binding site predicted in [6] is shown. B – alignment between the putative Ku-binding sites in the NRE-1 region of HIV-1 and MMTV, as well as some other sequences similar to MMTV NRE-1 [6].