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. 2016 Apr 19;15:67. doi: 10.1186/s12933-016-0378-5

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© von Scholten et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — IL-21R expression level on leukocyte populations in diabetic patients and healthy controls. The IL-21R expression on CD4⁺ T cells (a), CD8⁺ T cells (b), B cells (c) and CD68⁺ monocytes (d) is shown. Representative histogram analysis of IL-21R expression on CD19⁺, CD68⁺, CD4⁺ and CD8⁺ cells compared to the isotype antibody signal (e) that were first identified using the gating strategy from Figs. 1, 2 and Additional file 1: Figure S1. A total of 2 ml blood was analysed and the total number of each cell population was calculated as described in the “Methods” section. Each dot represents one individual and the horizontal line represents the mean value in each group. P values represent difference between groups assessed by t test