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. 2016 Apr 19;35:69. doi: 10.1186/s13046-016-0348-5

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© Jiang et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig 1 — Mir-138 expression was downregulated in human osteosarcoma tissues and cell lines. a Fold change of miR-138 expression in human osteosarcoma tissues and the adjacent normal tissues. ^# P < 0.01 compared with the normal. b Relative expression of miR-138 in the osteosarcoma tissues from the patients with metastases and non-metastases. ^# P < 0.01 compared with the non-metastases tissues. c Fold change of miR-138 expression in human osteosarcoma cell lines (MG-63, U2OS, SJSA-1, and SAOS-2) and the normal bone cell line (hFOB). ^# P < 0.01 compared with hFOB