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. 2016 Jan 27;213(10):1586–1595. doi: 10.1093/infdis/jiw032

Figure 5.

Figure 5.

Time to development of Pneumocystis pneumonia (PCP) in KEX1-immunized animals, compared with mock-immunized animals. Despite comparable immunosuppression, KEX1-immunized animals were significantly protected from developing PCP following simian/human immunodeficiency virus (SHIV) infection, compared with mock-immunized controls (P = .047, by Kaplan–Meier analysis). A diagnosis of PCP was made by detection of Pneumocystis DNA by polymerase chain reaction (first-round) analysis of bronchoalveolar lavage fluid and/or by detection of Pneumocystis in lung tissue by immunohistochemical analysis.