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Risk stratification of multiple myeloma by cytogenetic abnormalities
| High risk | Intermediate risk | Standard risk |
|---|---|---|
| Deletion 17p | t(4;14) | t(11;14) |
| t(14;16) | 1q gain | t(6;14) |
| t(14;20) | Metaphase deletion 13 | All other cytogenetic abnormalities not high- or intermediate-risk |
| GEP high risk signature | High plasma cell proliferative rate S-phase (≥3%) |
