Figure 1. DREAMTools library framework.

DREAM challenges are described at the DREAM website ( http://dreamchallenges.org) where researchers can get an overview of the past and current challenges. Each challenge has its own project page within the Synapse framework ( http://synapse.org) where details about the challenge are available. The final leaderboard showing benchmarks achieved at the end of the challenge are also shown in the Synapse project. DREAMTools provides a Python library that allows researchers to retrieve a template for each closed challenge and to easily score a prediction/template against the gold standard. In a few lines of code, the score of a prediction can then be compared to the official leaderboard, as illustrated in the example in the green box on the right hand side of the figure.