Table 4.

Hazard Ratio for All Diabetes Complications Stratified by Baseline Antipsychotic Treatment Pattern

Baseline	No or Irregular Use	Regular Use of Antipsychotics With Low Metabolic Risk	Regular Use of Antipsychotics With Intermediate or High Metabolic Risk	Regular Use of Combination Antipsychotic Treatment
During Follow-up Period
No or irregular use
Event/person-year, incidence	735/31 492, 23.3	124/4580, 27.1	157/6873, 22.8	97/4803, 20.2
Adjusted HR, 95% CI	reference	0.89 (0.62–1.28)	1.45 (1.08–1.96)*	0.94 (0.55–1.61)
Regular use of antipsychotics with low metabolic risk
Event/person-year, incidence	74/3453, 21.4	93/5487, 16.9	29/2099, 13.8	28/1459, 19.2
Adjusted HR, 95% CI	0.96 (0.73–1.27)	reference	0.93 (0.62–1.39)	1.15 (0.67–1.96)
Regular use of antipsychotics with intermediate or high metabolic risk
Event/person-year, incidence	102/5025, 20.3	36/1568, 22.9	136/8846, 15.4	42/2291, 18.3
Adjusted HR, 95% CI	0.80 (0.63–1.03)	1.04 (0.69–1.56)	reference	1.05 (0.64–1.72)
Regular use of combination antipsychotic treatment
Event/person-year, incidence	25/1153, 21.7	9/677, 13.3	31/1538, 20.1	27/1617, 16.7
Adjusted HR, 95% CI	0.86 (0.57–1.31)	0.62 (0.31–1.23)	1.42 (0.95–2.10)	reference

Note:*P value < .05.