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In vitro functionality of rs1478435 in SK-N-AS (A, B) and SN4741 (C, D). (A, C) Lower 2.5-kb SLC6A3 promoter activity conferred by T than by C allele (by ANOVA tests, N = 3–5). (B, D) Reduced enhancement by T. Student’s t tests: **P < .01; ****P < .0001 (data in A, C).
