Table 4.
Association of Imputed SLC6A3 Markers With SCZ in Caucasians
| Marker | BP | SLC6A3 Location | Prot. Allele | Case | Control | ChiSq | OR (95% CI) | P-Value | Adjusted P b |
|---|---|---|---|---|---|---|---|---|---|
| rs2975223 | 1443603 | Intron 1 | A | 0.3873 | 0.4351 | 5.190 | 0.8209 (0.6927–0.9729) | .02272 | .4401 |
| rs67175440 | 1443604 | Intron 1 | G | 0.3849 | 0.4332 | 5.199 | 0.8187 (0.6893–0.9724) | .02260 | .1445 |
| rs12652860 | 1453772 | 5′ promoter | A | 0.2676 | 0.3190 | 6.969 | 0.7799 (0.6483–0.9382) | .00830 | .0622 |
| rs1478435 a | 1454612 | 5′ promoter | T | 0.2124 | 0.2645 | 8.094 | 0.7500 (0.6150–0.9147) | .00441 | .0356 |
| rs10061889 | 1456803 | 5′ promoter | A | 0.2222 | 0.2741 | 7.458 | 0.7566 (0.6192–0.9246) | .00632 | .0477 |
| rs748209 | 1457554 | 5′ promoter | A | 0.2175 | 0.2714 | 8.308 | 0.7463 (0.6114–0.9109) | .00395 | .0319 |
| rs2937650 | 1458018 | 5′ promoter | A | 0.2175 | 0.2714 | 8.308 | 0.7463 (0.6114–0.9109) | .00395 | .0319 |
Note: aSelected for functional assessments.
aBold, P-value is less than .05 and considered statistically significant.