Figure 4.

MSCs increased AT-II cell proliferation. AT-II cell proliferation was evaluated by the Cell Counting Kit-8 assay under four different conditions. MSCs were observed to improve AT-II cell proliferation, and this effect was reduced by MSCs-KGF siRNA. ^*P<0.05 vs. AT-II cells (cytokines + PBS); ^†P<0.05 vs. AT-II cells (cytokines + PBS) or AT-II cells (cytokines + MSCs). MSCs, mesenchymal stem cells; AT-II cell, alveolar type II epithelial cell; KGF, keratinocyte growth factor; siRNA, small interfering RNA; PBS, phosphate-buffered saline; OD, optical density; Lipof, lipofectamine.