Figure 5. Effect of HIV co-infection on the diagnostic power of the tuberculosis score.
In GSE37250, GSE39939, and GSE39940, no significant difference was noted in the diagnostic power for other diseases versus active tuberculosis based on HIV status. In GSE37250, there was a decrease in ROC AUC from 0·96 to 0·89 in latent tuberculosis versus active tuberculosis in HIV-positive patients. ROC=receiver operating characteristic. AUC=area under the curve.