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. Author manuscript; available in PMC: 2016 Apr 20.
Published in final edited form as: J Autoimmun. 2015 Aug 21;64:113–124. doi: 10.1016/j.jaut.2015.08.002

Fig. 1.

Fig. 1

Age of onset of 80% of children with JIA with various combinations of HLA risk alleles. 80% of children with any 2 HLA DR risk alleles, HLA DPB1 and A2 alleles develop JIA by age 4.7 years. Adapted from Murray KJ, Moroldo MB, Donnelly P, Prahalad S, Passo MH, Giannini EH, et al. Age-specific effects of juvenile rheumatoid arthritis associated HLA alleles. Arthritis Rheum 1999; 42:1843–53.