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. 2016 Apr 20;11(4):e0153086. doi: 10.1371/journal.pone.0153086

Table 1. Percentages (%) of mouse embryos developing into different pre-implantation stages after microinjection of LIF-siRNA or scrambled-siRNA at the two-pronuclear stage.

Untreated (n = 51) Solution (n = 30) scramble (n = 87) LIF-siRNA (n = 24)
Two-cell 90.2 93.3 93.1 91.7
Four-cell 85.7 86.7 92.0 75.0
Morula 83.4 83.3 89.7 58.3a
Blastocyst 83.4 80.0 86.2 41.7a

aP<0.05 compared with the untreated group.