. 2016 Apr 20;11(4):e0153953. doi: 10.1371/journal.pone.0153953

Table 4. Main and interaction effects of clinical and psychosocial variables on patient-reported internalizing problems.

	Patient-reported internalizing problems
	Covariates		Clinical variables main effects		Psychosocial variables main effects		Interaction effects
	ΔR² = .02		ΔR² = .02		ΔR² = .37		ΔR² = .02
	ΔF_{(1, 291)} = 6.14^*		ΔF_{(2, 289)} = 2.34		ΔF_{(4, 285)} = 44.64^**		ΔF_{(4, 281)} = 2.96^*
	β	t	β	t	β	t	β	t
Children’s sex ^a	-.14	-2.48^*	-.14	-2.46^*	-.11	-2.31^*	-.10	-2.15^*
Treatment status ^b			-.03	-0.48	-.14	-2.79^**	-.13	-2.51^*
Current height deviation ^c			.13	2.16^*	-.04	-0.79	-.04	-0.75
Generic QoL					-.34	-6.29^**	-.49	-5.96^**
Specific QoL					-.37	-5.04^**	-.20	-1.98^*
Coping					-.01	-0.06	-.02	-0.36
Beliefs					-.09	-1.40	-.17	-2.35^*
Generic QoL ^* Treatment							.16	2.08^*
Specific QoL ^* Treatment							-.21	-2.66^**
Coping ^* Height deviation							.04	0.60
Beliefs ^* Height deviation							.12	1.88
Model summary	R² = .02		R² = .04		R² = .41		R² = .43
	F_{(1, 291)} = 6.14^*		F_{(3, 289)} = 3.63^*		F_{(7, 285)} = 28.01^**		F_{(11, 281)} = 19.39^**

^a Children’s sex: 0 –female, 1 –male

^b Treatment status: 0 –treated; 1 –untreated

^c Current height deviation: 0 –achieved normal height (> -2sd), 1 –current short stature (≤ -2sd).

^* p ≤ .05

^** p ≤ .01, two-tailed.