Fig 6. Increased ω-3 polyunsaturated fatty acid concentration following spaceflight.

Mass spectrometry-based metabolomics was performed and spectra corresponding to both saturated and unsaturated fatty acids were identified and chromatographic peaks quantified. Mann-Whitney analysis of results from n = 5 mice per group showed a significant increase in levels of ω-3 PUFAs in spaceflight mice as compared with AEM controls. **P < 0.01; data are mean ± SEM.