Table 2. Covariation and conservation mean ± standard deviation scores for known and control inter- and intramolecular, along with the percentage of conserved (and canonical), covarying (both double and single-sided) and invalid (non-canonical, gapped) basepairs in the same alignments.

Data set	Covariation	Conservation	% Basepairs covarying	% Basepairs conserved	% Basepairs invalid	Basepairs
rRNA–rRNA	0.06 ± 0.34	0.87 ± 0.19	0.07 ± 0.04	0.84 ± 0.02	0.10 ± 0.01	1504
snoRNA–rRNA	−0.03 ± 0.13	0.98 ± 0.06	0.01 ± 0.01	0.97 ± 0.03	0.02 ± 0.03	664
sRNA–mRNA	−0.03 ± 0.14	0.97 ± 0.08	0.01 ± 0.02	0.96 ± 0.06	0.03 ± 0.04	1879
Non-functional rRNA–rRNA	−0.17 ± 0.29	0.83 ± 0.18	0.06 ± 0.01	0.69 ± 0.23	0.24 ± 0.24	1500
Shuffled rRNA–rRNA	−0.46 ± 0.40	0.72 ± 0.24	0.05 ± 0.00	0.22 ± 0.00	0.73 ± 0.00	1504