Figure 4.
Characterization of sciRNA targets. (A) Venn diagram of target genes predicted in mESCs, testis and cerebellum. (B) Distribution of target cleavage sites (Deg-Seq peaks) in different types of regions of the transcriptome. CDS: coding sequence; NC exon: exon of non-coding transcript. Random: random positions from random transcripts (see Supplementary Methods). (C) Types of non-coding transcripts among sciRNA targets, prioritized as pseudogene > lncRNA > other. (D) Pearson correlation of target mRNA expression and sciRNA expression for four example categories of target genes (see Supplementary Methods).