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. Author manuscript; available in PMC: 2016 Apr 20.
Published in final edited form as: Cochrane Database Syst Rev. 2015 Apr 15;4:CD009660. doi: 10.1002/14651858.CD009660.pub3

Table 7.

Psychological therapies for parents of children and adolescents with cancer

Psychological therapies for parents of children and adolescents with cancer
Patient or population: Parents of children with cancer
Settings: Community
Intervention: Psychological therapies
Outcomes Probable outcome with control Probable outcome with intervention Relative effect (95% CI) No of Participants (studies) Quality of the evidence (GRADE) Comments
Parenting behaviour post-treatment (low scores indicate less adverse behaviour ratings) The mean parent behaviour post-treatment in the intervention groups was 0.2 standard deviations lower (0.36 to 0.04 lower) SMD −0.2 (−0.36 to −0.04) 836
(5 studies)
⊕○○○
very low1,2,3
Parenting behaviour at follow-up (low scores indicate less adverse behaviour ratings) The mean parent behaviour at follow-up in the intervention groups was 0.12 standard deviations lower (0.29 lower to 0. 05 higher) SMD −0.12 (−0. 29 to 0.05) 789
(5 studies)
⊕○○○
very low1,2,3
Parent mental health post-treatment (high scores indicate poor mental health) The mean parent mental health post-treatment in the intervention groups was 0.22 standard deviations lower (0.46 lower to 0. 01 higher) SMD −0.22 (−0. 46 to 0.01) 1010
(9 studies)
⊕○○○
very low1,2,4
Parent mental health at follow-up (high scores indicate poor mental health) The mean parent mental health at follow-up in the intervention groups was 0.18 standard deviations lower (0.32 to 0.04 lower) SMD −0.18 (−0. 32 to −0.04) 819
(6 studies)
⊕○○○
very low1,2,3
SMD: Standardised mean difference
GRADE Working Group grades of evidence
High quality: Further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: We are very uncertain about the estimate.
1

Majority of studies included in outcome have unclear or high risk of bias

2

Majority of studies did not have an active comparator

3

A significant proportion of studies did not report outcomes in published paper

4

Heterogeneity I2 > 45%