Table 3.
Factors Associated with Concordant Histologic, Endoscopic, and Symptom Response to Steroid Therapy
| Discordant (n = 98) | Concordant (n = 77) | p-value | |
|---|---|---|---|
| Age, mean years ± SD | 24 ± 17 | 29 ± 18 | 0.06 |
| White Race, n (%) | 77 (79) | 69 (90) | 0.05 |
| Male, n (%) | 71 (72) | 51 (66) | 0.37 |
| Adult ≥ 18 years, n (%) | 60 (61) | 50 (65) | 0.61 |
| Atopic Disease, n (%) | 47 (48) | 37 (48) | 0.96 |
| Asthma, n (%) | 26 (27) | 19 (25) | 0.75 |
| Food Allergy, n (%) | 25 (27) | 24 (34) | 0.34 |
| Baseline maximum eosinophil count (eos/hpf, mean ± SD) |
75 ± 63 | 78 ± 62 | 0.35 |
| Baseline symptoms | |||
| Abdominal Pain, n (%) | 11 (11) | 18 (24) | 0.03 |
| Chest Pain, n (%) | 8 (8) | 13 (17) | 0.08 |
| Dysphagia, n (%) | 70 (73) | 55 (72) | 0.94 |
| Heartburn, n (%) | 41 (43) | 26 (34) | 0.26 |
| Nausea, n (%) | 6 (6) | 12 (16) | 0.04 |
| Vomiting, n (%) | 25 (26) | 22 (29) | 0.67 |
| Food Impaction, n (%) | 30 (31) | 28 (37) | 0.44 |
| Baseline EGD Findings | |||
| Normal, n (%) | 7 (7) | 6 (8) | 0.85 |
| Rings, n (%) | 52 (53) | 37 (49) | 0.57 |
| Narrowing, n (%) | 25 (26) | 10 (13) | 0.04 |
| Stricture, n (%) | 23 (23) | 15 (20) | 0.55 |
| Furrows, n (%) | 58 (59) | 41 (54) | 0.49 |
| White Plaques, n (%) | 33 (34) | 22 (29) | 0.51 |
| Decreased Vascularity, n (%) | 33 (34) | 23 (30) | 0.63 |
| Crepe Paper, n (%) | 8 (8) | 4 (5) | 0.45 |
| Hiatal Hernia, n (%) | 9 (9) | 6 (8) | 0.74 |
| Dilation Performed, n (%) | 33 (34) | 14 (19) | 0.03 |
| Steroid Therapy Details | |||
| Budesonide, n (%) | 69 (70) | 60 (78) | 0.26 |
| Fluticasone, n (%) | 29 (30) | 17 (22) | |
| Budesonide dose, mean mcg ± SD | 1641 ± 673 | 1792 ± 709 | 0.18 |
| Fluticasone dose, mean mcg ± SD | 1244 ± 620 | 1310 ± 579 | 0.71 |