A, The group treated with anthracycline demonstrated significantly lower intrinsic functional connectivity between the left precuneus (LPCN) and several other default mode network regions compared with the nonanthracycline group. B, The anthracycline group also showed lower connectivity in these regions compared with the no-chemotherapy (no-CT) group. C, The nonanthracycline group showed lower connectivity between LPCN and right middle cingulate (RMCG) compared with the no-chemotherapy group. Color bars indicate effect size; LMEF, left medial frontal; LLP, left lateral parietal; RHIP, right hippocampus; RPCG, right posterior cingulate; RSFG, right superior frontal gyrus. Connectivity data are shown overlaid on a smoothed Montreal Neurological Institute space anatomic template using BrainNet Viewer.75