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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: IEEE Trans Ultrason Ferroelectr Freq Control. 2016 Feb 4;63(3):408–419. doi: 10.1109/TUFFC.2016.2525859

Fig. 15.

Fig. 15

Histological sections of the lesions produced with increasing numbers of therapy pulses per treatment location. In the control, all tissue structures and cells appeared structurally intact. After 50 pulses, large volumes of acellular debris were observed, with some pockets of structurally intact cells and nuclei remaining. After 200 pulses, the entire lesion appeared fractionated with few remaining intact nuclei. Beyond this (>500 pulses/treatment location), the treated volume appeared completely homogenized with no recognizable tissue structures and very few fragments of nuclear material.