Table 3. Treatment comparisons between the US and the UK.

	US		UK		US-UK Difference (95% CI)	p-value
Treatment	Total n	n(%)	Total n	n(%)
Hypertonic saline; n(%)
<18 years	13412	5489 (40.9)	39073	327 (8.4)	32.6 (31.4, 33.8)	<0.001
≥18 years	10803	5594 (51.8)	870	571 (14.8)	37.0 (35.6, 38.5)	<0.001
Any nebulised antibiotic, n(%)
<18 years	13412	6000 (44.7)	3907	1674 (42.9)	1.9 (0.1, 3.7)	0.036
≥18 years	10803	7079 (65.5)	3870	2396 (61.9)	3.6 (1.8, 5.4)	<0.001
rhDNase; n(%)
<18 years	13412	10360 (77.2)	3907	1382 (35.4)	41.9 (40.2, 43.5)	<0.001
≥18 years	10803	8126 (75.2)	3870	2009 (51.9)	23.3 (21.5, 25.1)	<0.001
Macrolides, n(%)
<18 years	13412	4505 (33.6)	3907	942 (24.1)	9.5 (7.9, 11.0)	<0.001
≥18 years	10803	7061 (65.4)	3870	2373 (61.3)	4.0 (2.3, 5.8)	<0.001