Figure 2. The effects of DS and PS on the proliferation of mitogen-stimulated mouse spleen mononuclear cells. (A) DS from DEX-treated pregnant BALB/c mice significantly suppressed the proliferation of PHA- and LPS-stimulated mononuclear cells in comparison with DS from PBS-treated pregnant BALB/c mice. (B) PS from DEX-treated pregnant BALB/c mice and PS from PBS-treated pregnant BALB/c had a similar inhibitory effect on PHA- and LPS-stimulated mononuclear cell proliferation. All data presented in these charts were obtained by the treatment of mouse spleen mononuclear cells with a 5% concentration of DS or PS. The stimulation index was calculated by dividing the optical density test of each group by the optical density control for each group. The results are expressed as mean±standard error of measurement from seven independent experiments. DS, decidual cell supernatant; PS, placenta cell supernatant; DEX, dexamethasone; PHA, phytohemagglutinin; LPS, lipopolysaccharides; PBS, phosphate-buffered saline. ^*p<0.05, ^**p<0.01 was used for the statistical analysis.