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. 2016 Apr 21;7:101. doi: 10.3389/fphar.2016.00101

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Copyright © 2016 Ji, Wei, Hao, Xing, Yuan, Wang, Xu and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Myocardial infarct size and cardiomyocytes apoptosis in I/R rats. (A) TTC staining for myocardial infarct size with representative tissue sectioning for SHAM, I/R, I/R + Alda-1, the ALDH2 activator, and Daidzin, the inhibitor. (B) The infarct size was expressed as a percentage of area at risk (P < 0.0001, One-way ANOVA). (C) TUNEL staining for myocardial tissue apoptosis. (D) Ratio of apoptosis (P < 0.0001, One-way ANOVA). n = 3/group. Representative TUNEL staining images are shown (magnification, 200×). Scale bar: 50 μm. Data are mean ± SD from 3 independent experiments. ^∗P < 0.05 vs. sham; ^#P < 0.05 vs. I/R.