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. 2016 Apr 7;2016:3745961. doi: 10.1155/2016/3745961

Figure 5.

Figure 5

Effect of rolipram on chloride/bicarbonate exchanger activity. (a) Changes in intracellular pH (pHi) in the ductal cells in the presence of rolipram (open circle) and control (closed black square). (b) Ductal chloride/bicarbonate exchanger (CBE) activity. The slope of pHi assessed CBE activity in the absence of Cl− at the beginning of time course (30~45 sec) and height to reach maximum pHi point from minimum point. The bars show the mean ± SEM (n = 3). (c) Changes of intracellular Cl− concentration. Ductal cells were loaded with MQAE dye and fluorescence was monitored in the presence of rolipram (closed gray square) and control (closed black square). The traces were measured with arbitrary MQAE intensity every 3 sec.