Table 1.
Odds ratio (OR) and 95% confidence interval (CI) of fecal immunochemical test (FIT) positive and compliance to colonoscopy by gender, age group, and FIT status in the Jiashan mass colorectal cancer screening program in China, 2007–2009.
| Gender | Age | FIT | Participant | Positive | OR1 (95% CI) | OR2 (95% CI) | Colonoscopy | OR1 (95% CI) | OR2 (95% CI) |
|---|---|---|---|---|---|---|---|---|---|
| n | n (%) | n (%) | |||||||
| Men | Age <55 | FIT1 | 6,435 | 219 (3.4) | 1.00 | 182 (83.1) | 1.00 | ||
| FIT2 | 5,314 | 196 (3.7) | 1.09 (0.89–1.32) | 1.00 | 162 (82.7) | 0.97 (0.58–1.62) | 1.00 | ||
| Both | 5,302 | 62 (1.2) | 0.34 (0.25–0.45) | 0.31 (0.23–0.41) | 54 (87.1) | 1.37 (0.60–3.12) | 1.42 (1.62–3.23) | ||
| Either | 6,447 | 353 (5.5) | 1.64 (1.38–1.95) | 1.51 (1.27–1.81) | 294 (83.3) | 1.01 (0.65–1.59) | 1.05 (0.66–1.66) | ||
| Age ≥55 | FIT1 | 5,352 | 327 (6.1) | 1.00 | 245 (74.9) | 1.00 | |||
| FIT2 | 4,589 | 253 (5.5) | 0.90 (0.76–1.07) | 1.00 | 196 (77.5) | 1.15 (0.78–1.70) | 1.00 | ||
| Both | 4,580 | 93 (2.0) | 0.32 (0.25–0.40) | 0.36 (0.28–0.45) | 73 (78.5) | 1.22 (0.70–2.13) | 1.06 (0.60–1.89) | ||
| Either | 5,361 | 487 (9.1) | 1.54 (1.33–1.78) | 1.71 (1.46–2.00) | 368 (75.6) | 1.04 (0.75–1.43) | 0.90 (0.63–1.29) | ||
|
| |||||||||
| Women | Age <55 | FIT1 | 6,921 | 297 (4.3) | 1.00 | 257 (86.5) | 1.00 | ||
| FIT2 | 5,918 | 224 (3.8) | 0.88 (0.74–1.05) | 1.00 | 198 (88.4) | 1.54 (0.87–2.72) | 1.00 | ||
| Both | 5,911 | 64 (1.1) | 0.24 (0.19–0.32) | 0.28 (0.21–0.37) | 57 (89.1) | 1.27 (0.54–2.97) | 1.07 (0.44–2.59) | ||
| Either | 6,928 | 457 (6.6) | 1.58 (1.36–1.83) | 1.80 (1.52–2.12) | 398 (87.1) | 1.05 (0.68–1.62) | 0.89 (0.54–1.45) | ||
| Age ≥55 | FIT1 | 5,667 | 304 (5.4) | 1.00 | 237 (78.0) | 1.00 | |||
| FIT2 | 5,065 | 242 (4.8) | 0.89 (0.74–1.05) | 1.00 | 198 (81.8) | 1.27 (0.83–1.95) | 1.00 | ||
| Both | 5,049 | 82 (1.6) | 0.29 (0.23–0.37) | 0.33 (0.26–0.42) | 66 (80.5) | 1.17 (0.63–2.15) | 0.92 (0.49–1.73) | ||
| Either | 5,683 | 464 (8.0) | 1.57 (1.35–1.82) | 1.77 (1.51–2.08) | 369 (79.5) | 1.10 (0.77–1.56) | 0.86 (0.58–1.28) | ||
|
| |||||||||
| Men | All | FIT1 | 11,787 | 547 (4.6) | 1.00 | 432 (79.0) | 1.00 | ||
| FIT2 | 9,903 | 449 (4.5) | 0.98 (0.86–1.11) | 1.00 | 358 (79.7) | 1.05 (0.77–1.43) | 1.00 | ||
| Both | 9,882 | 155 (1.6) | 0.33 (0.27–0.39) | 0.34 (0.28–0.40) | 127 (81.9) | 1.21 (0.76–1.91) | 1.15 (0.72–1.84) | ||
| Either | 11,808 | 841 (7.1) | 1.58 (1.41–1.76) | 1.62 (1.44–1.82) | 663 (78.8) | 0.99 (0.76–1.29) | 0.95 (0.71–1.26) | ||
|
| |||||||||
| Women | All | FIT1 | 12,588 | 600 (4.8) | 1.0 | 494 (82.2) | 1.0 | ||
| FIT2 | 10,983 | 459 (4.2) | 0.87 (0.77–0.99) | 1.0 | 396 (85.0) | 1.23 (0.88–1.70) | 1.0 | ||
| Both | 10,960 | 145 (1.3) | 0.27 (0.22–0.32) | 0.31 (0.26–0.37) | 123 (84.2) | 1.16 (0.71–1.89) | 0.95 (0.57–1.58) | ||
| Either | 12,611 | 914 (7.2) | 1.56 (1.40–1.74) | 1.79 (1.60–2.01) | 767 (83.3) | 1.08 (0.82–1.42) | 0.88 (0.65–2.20) | ||
|
| |||||||||
| Total | FIT1 | 24,375 | 1,148 (4.7) | 1.0 | 926 (80.7) | 1.0 | |||
| FIT2 | 20,886 | 915 (4.4) | 0.93 (0.85–1.01) | 1.0 | 754 (82.4) | 1.12 (0.90–1.41) | 1.0 | ||
| Both | 20,842 | 301 (1.4) | 0.30 (0.26–0.34) | 0.32 (0.28–0.37) | 250 (83.1) | 1.18 (0.84–1.64) | 1.05 (0.74–1.48) | ||
| Either | 24,419 | 1,762 (7.2) | 1.57 (1.46–1.70) | 1.70 (1.56–1.84) | 1,430 (81.2) | 1.03 (0.86–1.25) | 0.92 (0.75–1.13) | ||
FIT1, the first FIT; FIT2, the second FIT; OR1 using FIT1 as reference; and OR2 using FIT2 as reference.