Table 3.
Effect of Tamarindus indica L. tablets on serum biochemical markers of liver function in CCl4 induced hepatotoxicity in Sprague Dawley rats.
| Group | ALT (UI/L) | AST (UI/L) | ALP (UI/L) | GGT (UI/L) | TB (mg/100 mL) | TP (g/100 mL) |
|---|---|---|---|---|---|---|
| I | 32.56 ± 2.05b | 21.37 ± 0.59c | 187.32 ± 3.08d | 86.18 ± 3.86d | 3.09 ± 0.04d | 7.12 ± 0.47b |
| II | 326.78 ± 19.31a | 95.97 ± 4.41a | 426.53 ± 3.31a | 161.30 ± 7.90a | 6.57 ± 0.09a | 5.26 ± 0.37c |
| III | 36.33 ± 0.94b | 37.27 ± 5.64b | 204.56 ± 2.90c | 98.10 ± 1.40c | 4.84 ± 0.25c | 8.29 ± 0.22a |
| IV | 38.62 ± 0.98b | 38.67 ± 2.50b | 246.76 ± 3.10b | 111.10 ± 1.19b | 5.21 ± 0.17b | 7.41 ± 0.23b |
| V | 33.49 ± 0.91b | 25.38 ± 2.38c | 202.51 ± 4.96c | 99.09 ± 3.34c | 5.15 ± 0.06b | 8.33 ± 0.34a |
ALT: alanine aminotransferase, AST: aspartate aminotransferase, ALP: alkaline phosphatase, GGT: γ-glutamyl transpeptidase, TB: total bilirubin, and TP: total protein.
I: control group; II: CCl4 induced hepatotoxicity group; III: Silymarin treated group; IV and V: Tamarindus indica L. tablets treated groups at doses 100 mg/kg and 200 mg/kg, respectively.
Different letters on columns indicate significant statistical differences in Tukey HSD test.
Data are expressed as mean ± SD; n = 7.