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. 2016 Apr 21;6:24779. doi: 10.1038/srep24779

Figure 7. Impact of porcine liver matrices on T cell and B cell subpopulation proliferation and Th1/Th2 cytokine secretion in co-cultures in the presence of OKT3.

Figure 7

(a–f) The proliferation patterns of T cells, B cells and their subsets were analyzed using anti-human CD3, CD8, CD4, HLA-DR and CD19 antibodies. (g–k) Th1 and Th2 cytokine levels for TNF-α, IFN-γ, IL-5, IL-6 and IL-10 are shown for co-cultures of PBMCs alone or in combination with protein extracts of the porcine matrix. Negative controls without any proteins from the liver materials in OKT3-coated wells are included. Na = native liver; De = decellularized; GP = genipin; GA = glutaraldehyde. *p < 0.05 with respect to the native group; **p < 0.01 with respect to the native group; #p < 0.05 with respect to the decellularized group; ##p < 0.01 with respect to the decellularized group; op < 0.05 with respect to the control group. All data are given as the mean ± SEM.